Current Studies

The facts about participating in clinical research and our ongoing studies:

First and foremost your safety is our top priority. Participating in clinical research gives you access to the latest medical and scientific innovations in medicine as well as compensates the participant(s) for time and travel. Most importantly, you are advancing medical science by contributing to the development of vital new medicines and paving the way for these new medicines to reach the market.

Please let us know if you are interested in participating in a research study. Study participants receive medical care, lab tests, and study medication at no cost, and are compensated for their participation. Transportation can be provided.

For more information, please call: 954-366-0277.

 

CURRENTLY ENROLLING STUDIES

HOLLYWOOD NEUROLOGY

For more information, please call: 954-366-0277.

Axovant Sciences: Alzheimer’s Disease
A thirty-three week study of an adjunct treatment of a new drug with patients between 50 and 85 years old who are stable on donepezil therapy (Aricept).

Merck – APECS: Memory Loss
A two-year study with a new oral drug as a potential disease-modifying therapy in patients 50 and 85 years old who have been experiencing memory loss for a year.

Merck – 012: Alzheimer’s Disease
A 6-month study evaluating the effectiveness of a new oral medicine for those patients between 55 and 85 years old and already on a stable dose of Aricept for treating the symptoms of mild to moderate Alzheimer’s Disease.

Biogen/EMERGE: Alzheimer’s Disease
A two-year study to evaluate a potential disease modifying treatment given monthly by intravenous infusion on the effect of passive immunization on the progression of cognitive impairment/mild Alzheimer’s Disease in patients who are 55 to 90 years old.

Amgen – ARISE: Migraine Prevention
A 1 year study evaluating a monthly injection for the prevention of migraine headaches. Patients 18 to 65 years old can participate.

Dr. Reddy’s: Migraine Headaches
A fifteen week study of the tolerability of DFN-11 Injection (Sumatriptan 3 mg) in Episodic Migraine With or Without Aura in patients 18 to 65 years old.

Osmotica – ALLAY-LID I & II: Parkinson’s Disease
A 16 or 26 week study to evaluate the efficacy and safety of Amantadine HCI extended release tablets in Parkinson’s Disease subjects with Levodopa-Induced Dyskinesias.

Lilly: Migraine
A 16 month study evaluating the effectiveness of a study drug in patients 18 to 65 who suffer from migraine headaches with or without aura.

Sunovion: Post Stroke Stem cell study
Stem cell study for patients 18 to 75 years old with a motor deficit from a stroke at least 6 months old and no longer than 5 years ago. Study duration is approximately 1 year.

 

HOLLYWOOD PULMONARY

Lead Study Coordinator: Lucy Vargas
954-981-4491 / lvargas@infinityclinicalresearch.com

Forest – ASCENT COPD:   Moderate to Severe COPD with High Cardiovascular Risk
A three-year post-marketing study to evaluate the effect of aclidinium bromide (Tudorza Pressair) on long-term cardiovascular safety and COPD attacks in patients 40 years old or older who are current or former smokers, with moderate to very severe COPD and a history of cardiovascular or cerebrovascular disease and/or significant cardiovascular risk.  This medicine is already FDA approved!

Glaxo SmithKline – IMPACT:   Chronic Obstructive Pulmonary Disease
A one-year study comparing the efficacy, safety and tolerability of  the investigational fixed dose triple combination therapy fluticasone furoate / umeclidinium / vilanterol trifentate (FF / UMEC / VI) compared with one of the FDA approved fixed dose dual combinations of Breo Ellipta (fluticasone furoate / vilanternol), a medicine similar to Advair, and Anoro Ellipta (umeclidinium / vilanterol) a medicine similar to Spiriva plus a fast-acting broncho-dilator; all administered once-daily in the morning with a dry powder inhaler in patients 40 years old or older with chronic obstructive pulmonary disease who are current or former smokers of at least 10 years.

Pearl Therapeutics – COPD:   Moderate to Severe COPD
One year study to evaluate combination therapy of two or three FDA approved medications for the treatment of moderate or severe COPD, Participants must be 40-80 years of age with documented history of exacerbations.

 

PLANTATION CARDIOLOGY

Study Coordinator: Becky Nembhard
954-306-8163 / rnembhard@infinityclinicalresearch.com

ARTESIA: Population Health Research Institute: Sub-clinical atrial fibrillation
A multi-year study to compare an approved anticoagulant (“blood thinner”) and aspirin to reduce clotting in patients with devise-detected sub-clinical atrial fibrillation.

Boehringer-Ingelheim: CARMELINA: Cardiovascular
Cardiovascular outcomes in Type II diabetics with kidney disease. Approximately 2 year study comparing an approved diabetic medication to placebo as add-on therapy to standard of care.
One day trial: Patient questionnaire regarding their treatment of cholesterol with single blood draw.

CARMELINA: Boehringer-Ingelheim: Diabetics with a high risk of heart or kidney disease
A multi-year study to evaluate an approved Type II diabetes medication in diabetic patients with a high risk of heart and/or kidney disease.

Duke Clinical Research Institute: Patient Assessment of Lipid Management
One day trial: Patient questionnaire regarding their treatment of cholesterol with single blood draw.

Sanofi – ODYSSEY: Recent Acute Coronary Syndrome with Obstructive Coronary Disease
A five-year study comparing a novel new class of drug on the occurrence of cardiovascular events in patients at least 40 years old who have experienced an acute coronary syndrome (ACS) event (unstable angina or heart attack) and despite intensive lipid modifying or statin therapy, are not adequately controlled.

TACT: Armetheon: Chronic Anticoagulation (“blood thinners”)
Up to 2 years study  comparing a novel new Vitamin K antagonist (“blood thinner”) with warfarin in patients requiring long-term anticoagulation.

 

SUNRISE NEUROLOGY

Clinical Study Coordinators:
Michele Kroll Fistel, LPN, CCRC; Dalia Ramos, RMA, CCRP; Fanny Gully, CRC; Magdeli Ramos, CCRC

Acorda Therapeutics/Civitas – LIDS: Parkinson’s Disease with Levodopa Induced Dyskinesias
A 12-month long study to assess safety and efficacy of a Levodopa Inhalation Powder in Parkinson’s Disease Patients With Motor Response Fluctuations (OFF Phenomena) Compared to an Observational Cohort Control

Alder Biopharmaceuticals
Study to assess ALD403 in the prevention of migraine headache in frequent episodic migraineurs.

Amgen – 20120296 STRIVE: Migraine Prevention
Up to 71-week study to Evaluate the Efficacy and Safety of an investigation medication in Migraine Prevention. The planned length of participation in the study for an individual subject is up to 71 weeks, which includes the following:

  • Initial screening phase of up to 3 weeks
  • 4-week baseline phase
  • 24-week double-blind treatment phase

Celgene – Diabetic Peripheral Neuropathy
An Efficacy and Safety Study of Intramuscular Injection of Human Placenta-Derived Cells (PDA-002) in Subjects With Diabetic Peripheral Neuropathy

Biogen 109MS414 MITIGATE
An 18-week long study to evaluate whether montelukast can reduce the severity of GI events in subjects with relapsing forms of MS taking TECFIDERA®

CoLucid – SAMARAI
11-week long study of Lasmitadan compared to placebo in the Acute Treatment of Migraine

Daiichi Sankyo: Fibromyalgia
A 21-week long study with optional long-term, open label extension to test effectiveness of an investigational drug compared to an FDA approved drug on fibromyalgia pain.

Eli Lilly – AMARANTH: Early Alzheimer’s Disease (MMSE 21-30)
A 24-month long study to evaluate a potential disease modifying therapy, oral formulation, in patients between 55 and 85 years old with early Alzheimer’s disease.

Pfizer TANGO: Chronic Low Back Pain
56-week long, randomized, double-blind, placebo and active controlled study of the analgesic efficacy and safety of Tanezumab in subjects with chronic low back pain

Lundbeck – STARBEAM: Mild to Moderate Alzheimer’s disease (MMSE 12-22)
A 28-week long study with optional long term, open-label extension in patients with mild-moderate Alzheimer’s disease treated with donepezil as adjunctive therapy.

Mallinckrodt: Multiple Sclerosis
Observational study using H.P. Acthar Gel to treat patients with multiple sclerosis experiencing exacerbations

Merck: Mild to Moderate Alzheimer’s disease (MMSE 12-24)
A 29-33 week long study to evaluate the potential of an oral investigational medication on improving memory in mild to moderate Alzheimer’s patients, 55-85 years of age, currently taking donepezil.

Neurim Pharmaceuticals Ltd. – reCOGNITION Mild Alzheimer’s disease (MMSE 21-26)
This study is a Phase 2, randomized, placebo controlled, dose ranging study of piromelatine (5, 20, and 50 mg daily for 6 months) versus placebo to determine an effective dose based on efficacy (cognitive performance), safety and tolerability in patients with mild dementia due to AD.

Novartis – ASSESS: Relapsing-Remitting MS
A one-year study to compare efficacy and safety of 2 doses of oral Fingoli mod (Gilenya) to Copaxone in adults at least 18 years old with rela psing remitting multi ple sclerosis.

Sanofi IVSS: OBS14379
A prospective observational cohort study in adult patients with relapsing multiple sclerosis to assess patient safety during and after LEMTRADA® (alemtuzumab) infusions of the first treatment course

Seratrials – 05035
One time blood draw for patients with multiple sclerosis – Amex gift card to those that qualify. There are a few projects: (1) MS with EDSS 1.5 or less (2) MS with EDSS 3.0 or more (3) RRMS currently taking Copaxone

Sun Pharma – SPASTICITY: Spasticity Due to MS
A 22-week study evaluating a new formulation of extended release baclofen in patients 18 years old and older with spasticity due to multiple sclerosis.

Sun Pharma – SPASTICITY OL: Spasticity Due to MS
A long-term safety study evaluating a new formulation of extended release baclofen in patients 18 years old and older with spasticity due to MS, who completed 26 weeks of treatment in the spasticity trial.

Suven Life Sciences Ltd: Moderate Alzheimer’s disease (MMSE 12-20)
26-week long study to evaluate the safety and efficacy of SUVN-502 with donepezil and memantine for the treatment of moderate Alzheimer’s disease.

TransTech Pharma: Mild Alzheimer’s Disease (STEADFAST) (MMSE 21-26)
An 18-month long study testing the efficacy and safety of an investigational medication on improving memory in patients with mild Alzheimer’s disease, age 50 and over, currently taking AChEI (donepezil, rivastigmine, galantamine) or memantine.